Fig. 7

Photomicrographs of sections in the liver tissues of different groups of the African-Egyptian toad treated with different nanomaterials: (a) A section in the group treated with group B, showing vacuolar degeneration of hepatocytes (long arrow) and activation of melanomacrophages (short arrow). (b) A section in the group treated with group C, showing vacuolar degeneration of hepatocytes (long arrow) and activation of melano-macrophages (short arrow). (c) A section in the group treated with group C showing central vein congestion (long arrow) and hepato-cellular vacuolation (short arrow). (d) A section in the group treated with group D, showing focal area of mononuclear inflammatory cells infiltration (arrow). (e) A section in the group treated with group E showing portal area fibrosis and mononuclear inflammatory cells infiltration (short arrow), congestion of portal blood vessels(long arrow). (f) A section in the group treated with group F, showing mild hepatocellular degeneration (short arrow), mild congestion of central vein (long arrow) and activation of melano-macrophages (white arrow). (g) A section in the group treated with group F, showing mononuclear infiltration (arrow). (h) A section in the group treated with group G, showing moderate vacuolar degeneration of hepatocytes (short arrow) with central vein congestion (long arrow). (i) A section in the group treated with group G, showing focal areas of mononuclear inflammatory cells infiltration (long arrows) and activation of melano-macrophages (short arrow). (j) A section in the group treated with group H, showing mild hepatocellular vacuolation (long arrow), few mononuclear infiltration (white arrow) and activation of melanomacrophages (short arrow). (H & E X400)