Fig. 1

Photomicrographs of sections in kidney tissues of different groups of rats treated with different nanomaterials: (a) A section in the control group showing normal histological structure of renal corpuscles (black arrow) and renal tubules (white arrow) (H & E X400). (b) A section in the group treated with chitosan nanoparticles B, showing interstitial mononuclear inflammatory cells infiltration (arrow) (H & E X400). (c) A section in the group treated with chitosan nanoparticles B, show necrosis of tubular lining epithelium (black arrow) and congestion of inter-tubular blood capillaries (white arrow) (H & E X400). (d) A section in the group treated with chitosan nanoparticles C, note vacuolation of endothelial lining of glomerular tuft (black arrow) with interstitial mononuclear inflammatory cells infiltration (white arrow) (H & E X400). (e) A section in the group treated with chitosan nanoparticles C, reveal heavy infiltration of interstitial tissue with mononuclear inflammatory cells (arrow) (H & E X200). (f) Higher magnification of the previous photo showing interstitial mononuclear inflammatory cells infiltration (arrow) (H & E X400). (g) A section in the group treated with chitosan nanoparticles C, show mononuclear inflammatory cells infiltration (black arrow) with renal tubular necrosis (white arrow) (H & E X400). (h) A section in the group treated with chitosan nanoparticles C, note vacuolar degeneration and necrosis of tubular lining epithelium (arrow) (H & E X400)