Table 1 Patient characteristics of all dogs included in the study (n = 45)

Total number of dogs

 for IHC analyses

 for NLR analysis

14

9

12

14

8

13

12

10

9

5

5

–

–

Age^†, in years

 median [range]

10.3 ^A

[7.3–12.8]

10.0 ^A

[4.7–13.2]

9.2 ^A,B

[1.8–12.0]

5.0^B

[2.0–10.0]

0.0431

Weight^†, in kg

 median [range]

20.9 ^A

[4.7–45.0]

23.5 ^A

[7.0–37.0]

35.3^B

[19.6–47.0]

21.8 ^A

[5.2–27.0]

0.0258

Neuter status^†, n (%)

 intact / neutered male

4 (29%) / 10 (71%)^A

10 (71%) / 4 (29%)^A,B

10 (83%) / 2 (17%)^B

5 (100%) / 0^B

0.0026

Breed

 pure-bred

 mixed breed

8 (57%)

6 (43%)

9 (64%)

5 (36%)

8 (67%)

4 (33%)

4 (80%)

1 (20%)

0.8200

Sample type

 USGTC

 surgical biopsy

 post-mortem

11 (79%)

3 (21%)

0

7 (50%)

7 (50%)

0

9 (75%)

3 (25%)

0

0

0

5 (100%)

–

NSAID treatment

 treatment-naïve

 prior NSAID treatment

8 (57%)

6 (43%)

7 (50%)

7 (50%)

9 (75%)

3 (25%)

–

–

Urine culture^$

 positive

 negative

1 (14%)

6 (86%)

7 (64%)

4 (36%)

4 (67%)

2 (33%)

–

–

Prostatic tissue culture^#

 positive

 negative

1 (12%)

7 (88%)

5 (56%)

4 (44%)

0

2 (100%)

–

Survival time^†, in days

 median [range]

14 ^A

[0–665]

682^B

[6–2,146]

1,741 ^C

[249–3,230]

–

< 0.0001