Fig. 1From: Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cellsPalmatine suppresses tumor progression in an in vivo CMT-U27 mouse xenograft model. A Tumor development at 21 days after intraperitoneal injection of Palmatine (50 mg/kg) and DMSO in PBS (control) in BALB/c nude mice. The dotted lines in the magnified images demarcate CMT masses. B Comparison of tumor volume in treatment group and control group over 21 days. C Comparison of the weight of tumors harvested from treatment and control group after 21 days of injection. Unless otherwise denoted: n = 5 each group. Values are mean ± SD. ** p < 0.01; *** p < 0.001 versus control. Con., control; Pal., palmatineBack to article page