Table 1 Rabbit models of hip mechanical osteoarthritis using the knee in extension
From: Mechanical osteoarthritis of the hip in a one medicine concept: a narrative review
Type of Immobilization | Sample Size (limbs) | Rabbits’ Age (days) | Immobilization’s Duration (weeks) | Sequela | References |
|---|---|---|---|---|---|
Knee extension using a compression arthrodesis device | - | - | - | Increased cartilage thickness Sclerotic thickened trabecula Bone cysts Degenerated disintegrating articular cartilage | [143] |
Knee extension, right limb with a splint and left limb with a padded plaster-of-Paris splint | - | 42 – 56 | 6 | Excessive femoral retroversion Round ligament hypertrophy Posterior Capsule Inversion Oedema Capsular fibrosis | [141] |
Plastic tube with the knee extension (one/both limbs) | n = 87 | 7 – 56 | 1—8 | Luxation Subluxation Coxa Vara | [139] |
Unilateral knee extension using a Kirschner wire | n = 60 | 7 – 21 | - | Luxation Subluxation | |
Right knee extension using a cast | n = 7 |  ~ 19 | 1.5 | Luxation Flattening of the articular cartilage Permanent tissue metaplasia | [140] |
n = 6 |  ~ 33 | 1.5 | |||
Left knee extension using a cast plaster | n = 9 | 28 | 2 | Increased cartilage thickness Capsular fibrosis Chondrocyte necrosis | [142] |
n = 9 | 4 | ||||
n = 9 | 6 | ||||
Unilateral knee extension using a cast plaster | n = 6 | 28 | 2 | Chondrocyte apoptosis | [137] |
n = 5 | 4 | Chondrocyte apoptosis Subluxation | |||
n = 5 | 6 | Luxation |