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Table 1 Abortions and premature deliveries after whole herd vaccination and revaccination with RB51 in Segovia (Spain)a

From: A review of three decades of use of the cattle brucellosis rough vaccine Brucella abortus RB51: myths and facts

A. In brucellosis free herds from which RB51 was isolatedb

Herdsc

Abortions and premature deliveries/no. of cows (%)

in the herd

in pregnant

A

1/41 (2.4)

1/10 (10)

B

5/50 (10)

5/20 (25)

C

9/110 (8.1)

9/50 (18.0)

D

16/150 (10.6)

16/100 (16.0)

E

17/135 (12.6)

17/110 (15.4)

F

19/122 (15.6)

19/95 (20.0)

G

29/126 (23)

29/60 (48.3)

H

22/70 (31.4)

22/58 (37.9)

TOTAL

804/118 (14.7)

503/118 (23.4)

B. In herds of unknown individual brucellosis sanitary status at vaccination not submitted to bacteriological analyses

Municipalitiesc, d

Abortions and premature deliveries/no. of cows (%)

in the municipality

in pregnant

I

24/217 (11)

24/136 (17.6)

J

85/516 (16.5)

85/381 (22.3)

K

29/202 (14.3)

29/292 (21.4)

K

50/292 (17.1)

50/205 (24.3)

L

94/534 (17.6)

94/367 (25.6)

M

32/150 (21.3)

79/150 (40.5)

N

53/301 (17.6)

53/197 (26.9)

O

42/ 370 (11.3)

42/205 (20.5)

P

26/291 (8.9)

26/209 (12.4)

Q

63/480 (13.1)

63/270 (23.3)

R

106/1108 (9.6)

106/679 (15.6)

S

105/586 (17.9)

105/441 (23.8)

T

126/553 (22.8)

126/438 (28.7)

TOTAL

835/5600 (14.9)

835/3742 (22.3)

  1. aIn 2009 and 2010, crossbred cows of extensively reared herd were inoculated and then re-inoculated 6 months later with full subcutaneous doses of RB51 irrespective of the age and reproductive condition. Reproductive data were recorded regularly in all herds
  2. bRepresentative samples (vaginal swabs and milk) from cows suffering abortion/premature delivery were cultured on both CITA’s and Farrell’s media and the isolates identified as RB51 by standard procedures and Bruce-ladder PCR
  3. cHerds/municipalities identification replaced by capital letters
  4. dAltogether, 90 herds