Fig. 8

HLA-DR⁺ Cells. The mean percentage of the immunolabeling fraction of HLA-DR⁺ macrophages significantly decreased as the stage of granuloma increased from stage I to stage IV showing similar kinetics as iNOS⁺ cells. The HLA-DR⁺ immunolabeling fraction was higher in the early-stage granulomas compared with the late stages, with a significant difference between stage I and stage II both with respect to stage IV) (** =P < 0.002)