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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Monitoring the immune response of macrophages in tuberculous granuloma through the expression of CD68, iNOS and HLA-DR in naturally infected beef cattle

Fig. 5

Expression of iNOS+ immunolabeling in (a): stage I and (b): stage II granulomas in the lymph node of beef cattle naturally infected with Mycobacterium. Strong positive expression was observed within the cytoplasm of macrophages (arrows) and multi-nucleated giant cells (arrowheads). (IHC, 100 μm). (c): iNOS+ macrophages forming a peripheral rim surrounding the necrotic center of the stage III granuloma (arrows). (d) Expression of iNOS+ macrophages in a stage IV granuloma (arrows). (IHC, 100 μm). The expression of iNOS+ macrophages (arrowhead) can be seen surrounding the necrotic center in the outer layer of the granuloma. (IHC, 200 μm)

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BMC Veterinary Research

ISSN: 1746-6148

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