Fig. 4

Antigenic epitope analysis of the FimH proteins of type 1 fimbriae from 4 different serotypes of avian pathogenic E.coli. The horizontal axis shows the residue number in the mature peptide; the vertical axis shows the surface probability plot. The antigenic epitopes are basically the same: A represents CHNDYPETITDY at positions 65–76; B represents NSRTDKPW at positions 117–124, which is the epitope for the monoclonal antibody 7C2; and C represents QTNNYNSDD at positions 154 to 162, which is the epitope for the monoclonal antibody 7D8. The antigenic epitope patterns were generated using Protean in DNA-star software