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Table 2 Definitions of fever in experimental S. suis pig infections conducted in the years 2000—2021

From: A critical review on experimental Streptococcus suis infection in pigs with a focus on clinical monitoring and refinement strategies

Study type

Experimental infection

Body temperature threshold of fever

Reference

Age of pigs in weeks

Serotype

Route

model

6–7

2

i.n.

 ≥ 41°C

[34]a

7

2

i.v.

[117]

path.

4–5

2

i.n.

 

[83]b

path.

4

2

i.n.

 ≥ 40.5°C

[57]

4–5

2

i.n.

[43]c

4–5

2

i.n.

[87]d

5

7

i.v.

[23]d

8

2

i.n.

[25]d

5–6

2

i.n.

[41]c

3

2

i.v.

[46]c

7–8

2

i.n.

[83]

vac.

8

14

i.n.

[24]d

8–9

9

i.v.

[51]d

8–9

2, 7

i.v.

[48]

7–8

2

i.n.

[30]e

9

2

i.n.

[113]d

9

9

i.v.

[81]d

6, 8

2

i.v.

[44]d

9

2, 9

i.n., i.v.

[82]d

7–8

2, 9

i.v.

[54]d

2–3

2

i.n.

[36]

model

1–2

2

i.n., i.v.

 > 40.0°C

[47]

path.

6

2

s.c.

[78]f

6

2

aerosolic

[55]g

0–1

2

i.n.

[35]

1

2

i.n., i.v.

[118]

3–4

2

i.n.

[37]

vac.

5

1, 2

i.p.

[89]f

8

2

i.v.

[67]

4

2

s.c.

[60]

8

2

i.v.

[68]

vac.

8–9

1

i.p.

 > 38.5°Ch

[77]

  1. model study on establishment of an infection model, path. study on pathogenesis, vac. study on vaccination
  2. a > 41°C
  3. b ≥ 41°C only for weaners
  4. c > 40.5°C
  5. ddefined as high fever
  6. e ≥ 40.2°C defined as fever and ≥ 40.5°C as high fever
  7. f ≥ 40°C
  8. gdefined as elevated body temperature
  9. hmeasured as ear temperature