Fig. 1

Age (A), infection status (B), S. suis serotype (C) and application route (D) in the reviewed publications on experimental pig infections (n = 68). In case of pigs of various ages (A), different serotypes (cps) (C) or infection routes (D) were used within one published study, it is listed under all respective categories. All mutants used in the reviewed studies were generated from serotype 2 wildtype strains. C. The pathogen status refers to the S. suis status of pigs (B). Pigs with a different immunity status e.g. caesarean-derived and colostrum-deprived (CDCD) pigs, that lack maternal immunity, as well as conventional pigs with potential background immunity were used. In some publications the S. suis pathogen status (n = 2/68) or serotypes (n = 2/68) of the challenge strain was not mentioned (n.m.)