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Table 1 The diagnostic performance of CILP1 according to the cut-off value

From: Can cartilage intermediate layer protein 1 (CILP1) use as a novel biomarker for canine myxomatous mitral valve degeneration levels or not?

 

CILP1 < 1.068 ng/mL

CILP1 > 1.068 ng/mL

P-value

Dogs (N)

13

14

 

Age (years)

9.75 ± 1.70

11.75 ± 2.52

0.6778

Heart rate (bpm)

124.00 ± 12.56

145 ± 28.84

0.4298

Blood pressure (mmHg)

130.00 ± 14.14

142.37 ± 22.01

0.3304

Murmur grade

4 ± 0.81

4.33 ± 0.70

0.0671

Radiology

 VHS

10.72 ± 0.66

10.88 ± 0.85

0.0150*

 Vlas

2.45 ± 0.59

2.36 ± 0.43

0.0205*

Echocardiology

 LVFS

59.52 ± 4.52

54.80 ± 9.93

0.7287

 LVIDdn

22.82 ± 2.14

22.43 ± 3.50

0.0005**

 LVIDsn

9.25 ± 0.81

10.31 ± 2.53

0.1037

 LA/Ao

1.66 ± 0.45

1.79 ± 0.49

0.0296*

 E-wave

92.70 ± 17.42

84.70 ± 23.67

0.8238

 E/A

0.98 ± 0.22

0.95 ± 0.26

0.3137

  1. CILP1 Cartilage intermediate layer protein 1, VHS Vertebral heart size, Vlas Vertebral left atrial score, LVFS Left ventricular fraction shortening, LVIDdn Left ventricular end diastolic diameter normalized for body weight, LVIDsn Left ventricular end systolic diameter normalized for body weight, LA/Ao Left atrial to aortic root ratio, E Early diastolic inflow velocity, A late diastolic inflow velocity, NT-proBNP N-terminal pro-B-type natriuretic peptide (NT-proBNP)
  2. *P < 0.05
  3. **P < 0.001
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BMC Veterinary Research

ISSN: 1746-6148

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