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Table 1 Examination scheme

From: The effect of treatment with pimobendan in dogs with preclinical mitral valve disease – a placebo-controlled double-blinded crossover study

 

first treatment period

second treatment period

baseline

day 90

day 180

baseline

day 90

day 180

sequence-group AB

A

A

B

B

sequence-group BA

B

B

A

A

  1. Each treatment period included follow-up investigations at day 90 and 180. A stands for the treatment with pimobendan; B stands for the treatment with placebo. Dogs in sequence-group AB received pimobendan in the first period and placebo in the second period. In sequence-group BA, the order was reversed. A washout period in between the two treatment periods was included