Fig. 4From: Pharmacokinetics and pharmacodynamics of enrofloxacin treatment of Escherichia coli in a murine thigh infection modelingIn-vivo ENR PD studies via murine neutropenic thigh infection model. Each symbol shows the mean value of thigh bacterial infection from five infected mice (Escherichia coli Heilong 15). Twelve dose regimens of ENR were used to treat the E. coli Heilong 15 infection. The variations in the log10 number of colony-forming unit (CFU)/thigh were evaluated in the beginning and post 24 hrs of treatment. Data points under the horizontal dashed line indicate killing and points above the horizontal dashed line showed growth and developmentBack to article page