Skip to main content

Table 1 Repeatability and reliability for fasting indices obtained from insulin and glucose concentrations measured on two consecutive days in 60 horses

From: Evaluation of fasting plasma insulin and proxy measurements to assess insulin sensitivity in horses

Variable Day 1 Median (IQR) Day 2 Median (IQR) CV% (CI) ICC CR% Paired t-test (between-test days) P value
Insulin sensitivity:
 1/insulin (mL/µIU) 0.088 (0.032–0.22) 0.076 (0.032–0.17) 23.8 (19.2–27.7) 0.95 65 0.10
 RISQI ([µIU/mL]−0.5) 0.30 (0.18–0.47) 0.28 (0.18–0.41) 12.2 (9.7–14.2) 0.95 33 0.14
 QUICKI 0.33 (0.28–0.39) 0.32 (0.28–0.37) 3.9 (2.9–4.6) 0.94 10 0.06
β-cell response:
 FI (µIU/mL) 11.4 (4.7–31.9) 13.2 (6.0–31.5) 23.8 (19.2–27.7) 0.95 65 0.11
 MIRG ([µIU]2 /[10\(\times\)mL\(\times\)mg) 4.9 (3.1–8.5) 13.2 (6.0–8.8) 17.5 (13.0–21.1) 0.89 47 0.03
 HOMA-β 126 (75–306) 125 (81–257) 25.3 (21.3–28.7) 0.91 70 0.26
  1. RISQI reciprocal of the square root of insulin; QUICKI quantitative insulin sensitivity check index; FI fasting insulin concentration; MIRG modified insulin-to-glucose ration; HOMA-β homeostatic model assessment of β-cell function; IQR interquartile range; CV coefficient of variation; ICC intraclass correlation coefficient; CR coefficient of repeatability
\