Time (h) | saline | 0.25 mg/kg | 0.5 mg/kg | 1.0 mg/kg |
---|---|---|---|---|
Baseline | 2.4 ± 1.2 | 2.4 ± 1.4 | 2.5 ± 1.3 | 3.0 ± 1.4 |
0.5 | 1.9 ± 0.4 | 2.6 ± 0.5 | 2.6 ± 1.1 | 2.5 ± 1.4 |
0.75 | 2.4 ± 0.9 | 2.3 ± 1.0 | 2.6 ± 0.5 | 2.0 ± 0.9* |
1 | 2.5 ± 1.1 | 2.6 ± 0.5 | 2.9 ± 1.4 | 2.1 ± 0.4* |
2 | 2.3 ± 0.9 | 2.6 ± 1.0 | 2.5 ± 0.8 | 2.1 ± 0.8* |
4 | 1.9 ± 0.6 | 2.6 ± 1.0 | 2.4 ± 0.9 | 2.5 ± 1.4 |
6 | 2.3 ± 0.9 | 2.1 ± 0.9 | 2.4 ± 1.3 | 2.6 ± 0.5 |
8 | --- | 3.0 ± 1.2 | 3.1 ± 1.6 | 1.9 ± 0.6* |
24 | --- | 2.7 ± 1.3 | 2.7 ± 1.1 | 2.8 ± 1.2 |