Meperidine concentration (ng/mL) | Normeperidine concentration (ng/mL) | |||||
---|---|---|---|---|---|---|
0.25 mg/kg(n = 7) | 0.5 mg/kg(n = 8) | 1.0 mg/kg(n = 8) | 0.25 mg/kg(n = 7) | 0.5 mg/kg(n = 8) | 1.0 mg/kg(n = 8) | |
4 hours | 135.2 ± 53.5 | 993.5 ± 1822.7 | 1142.6 ± 912.9 | 153.1 ± 120.4 | 956.8 ± 1646.6 | 1217.8 ± 1319.0 |
24 hours | ND | 1.51 ± 0.82 | 4.42 ± 5.89 | 1.13 ± 0.17 (n = 3) | 1.80 ± 0.60 | 4.70 ± 5.67 |
48 hours | ND | ND | ND | ND | 0.37 ± 0 (n = 1) | 0.48 ± 0.12 (n = 3) |
72 hours | ND | ND | ND | ND | ND | ND |
96 hours | ND | ND | ND | ND | ND | ND |