Table 2 Values obtained from morphometric analysis of ECM components
CONTROL | ISCHEMIA WITHOUT REPERFUSION | 1-WEEK REPERFUSION | 1-MONTH REPERFUSION | ||||
|---|---|---|---|---|---|---|---|
NECROTIC | SALVAGED | NECROTIC | SALVAGED | NECROTIC | SALVAGED | ||
Collagen I (%) | 20.3 ± 10.1 | 24.3 ± 6.7 | 18.9 ± 12.1 | 53.0 ± 10.1** | 18.1 ± 12.0 | 67.1 ± 3.8** | 23.0 ± 3.1 |
Collagen III (%) | 16.0 ± 9.3 | 21.9 ± 8.5 | 21.6 ± 8.4 | 24.6 ± 8.5 | 14.5 ± 8.5 | 36.6 ± 14.6* | 17.9 ± 7.7 |
Elastic fibers (%) | 6.7 ± 1.9 | 11.2 ± 3.1* | 9.1 ± 1.2* | 20.3 ± 6.2** | 13.6 ± 7.5 | 16.4 ± 3.0** | 12.6 ± 7.4 |
GAG (%) | 10.9 ± 7.1 | 5.9 ± 1.4 | 5.1 ± 1.3 | 29.2 ± 5.0** | 16.4 ± 10.0 | 25.4 ± 8.3** | 14.1 ± 6.3 |
SPARC (%) | 2.5 ± 0.6 | 0.4 ± 0.4 | 2.1 ± 0.5 | 6.9 ± 2.0** | 1.4 ± 0.9 | 6.6 ± 1.2** | 1.2 ± 0.3 |
Perlecan (%) | 0.7 ± 0.4 | 0.7 ± 0.2 | 0.9 ± 0.2 | 0.3 ± 0.2 | 0.1 ± 0.2 | 1.1 ± 0.7 | 0.4 ± 0.4 |
Laminin (%) | 8.7 ± 0.9 | 19.8 ± 1.4** | 19.5 ± 6.2** | 14.3 ± 1.5** | 11.5 ± 1.3* | 17.7 ± 1.1** | 5.5 ± 4.2 |
Fibronectin (%) | 0.1 ± 0.1 | 2.0 ± 0.8** | 0.5 ± 0.4* | 13.3 ± 9.8* | 0.6 ± 0.7 | 7.2 ± 4.1** | 0.4 ± 0.6 |