Table 1 Stem cells classification [1, 3, 4, 7, 8]
From: Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?
| Â | ESC | iPSC | MSC |
|---|---|---|---|
Origin | Derived from the inner cell mass of the pre-embryonic blastocyst | Derived from reprogrammed donor cells by exposure to transcription factors | Derived from tissues of endodermal, mesodermal and ectodermal lineages |
Plasticity | Totipotents | Pluripotents | Multipotents |
Differentiation potential | Endodermal, mesodermal and ectodermal tissues | Endodermal, mesodermal and ectodermal tissues | Mesodermal tissues |
Risk of tumorigenesis | Yes | Yes | No (minimal) |