A genetic variant of CYP2R1 identified in a cat with type 1B vitamin D-dependent rickets: a case report

BMC Veterinary Research

Table 3 Serum biochemistry and the doses of the vitamin D analogue and calcium gluconate administered during treatment

Day	Serum calcium (reference range: 2.05–3.02 mmol/L)	Ionized calcium (reference range: 1.20–1.35 mmol/L)	Serum inorganic phosphorus (reference range: 0.84–1.94 mmol/L)	Serum alkaline phosphatase (reference range: 38–165 U/L)	Serum creatine kinase (reference range: 89–312 U/L)	Calcium gluconate 8.5% treatment (ml/kg/h CRI)	Alphacarcidiol treatment (μg/kg PO)	Calcitriol treatment (ng/kg PO)
1	1.55	0.80	2.10	2262	2462	1.0 ml/kg IV several times		―
2	1.05	0.42	2.91	―	―	1.0	0.03 q8h	―
3	1.62	0.76	―	―	―	3.0	0.03 q8h	―
4	1.45	0.81	2.00	1386	1729	3.0	0.03 q8h	―
5	1.87	―	―	―	―	2.5	0.06 q8h	―
6	2.45	―	―	―	―	2.2	0.06 q8h	―
7	2.17	―	―	―	―	2.0	0.09 q8h	―
8	2.15	0.84	―	―	―	1.8	0.09 q8h	―
9	2.10	―	1.91	358	295	1.4	0.12 q8h	―
10	1.90	―	―	―	―	1.0	0.15 q8h	―
11	1.85	0.93	2.13	315	―	1.0	0.37 q8h	―
12	1.82	―	―	―	―	Discontinued	0.56 q8h	―
13	2.10	―	―	―	―	―	0.56 q8h	―
14	2.17	―	―	―	―	―	1.00 q8h	―
15	2.10	―	―	―	―	―	1.00 q8h	―
16	2.17	0.88	1.94	―	―	―	1.00 q8h	―
28	1.87	0.84	2.00	1615	907	―	1.00 q8h	―
47	2.05	―	2.07	1436	275	―	1.00 q12h	―
82	2.35	―	1.94	848	―	―	1.00 q12h	―
121	2.30	1.02	1.87	335	218	―	Discontinued	3.5 q24h
142	2.17	0.97	1.71	297	284	―	―	3.0 q24h
186	2.55	1.27	1.78	―	―	―	―	2.8 q24h
207	2.64	1.27	1.69	―	―	―	―	2.6 q24h

ISSN: 1746-6148