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Table 1 Effect of the chemical blockers on the intracellular invasion of Yersinia ruckeri

From: Invasion and replication of Yersinia ruckeri in fish cell cultures

Blocker

Working concentration

Average CFU/ml

Standard deviation

Significance

Percentage inhibition

Control

–

3.9 × 104

2.35 × 104

–

–

Cytochalasin D

2 μM

4.8 × 102

1.7 × 102

P < 0.05

98.8%

TAE 226

10 μM

2.4 × 104

1.6 × 104

P < 0.05

39.0%

Vinblastine

10 μM

3.4 × 103

1.1 × 103

P < 0.05

91.5%

Genistein

1 mM

4.9 × 103

2.2 × 103

P < 0.05

87.5%

Colchicine

2 μM

1.7 × 103

1.3 × 103

P < 0.05

95.8%

N-acetylcysteine

5 mM

0.0

0.0

P < 0.05

100.0%

  1. The numbers presented are based on Y. ruckeri strain ATCC 29473 infection a Chinook Salmon Embryo cell culture
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BMC Veterinary Research

ISSN: 1746-6148

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