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Table 4 Patient response and post-treatment histopathology

From: Safety and efficacy of targeted hyperthermia treatment utilizing gold nanorod therapy in spontaneous canine neoplasia

Patient

Response

Histopath pre-treatment

Histopath post treatment

Post-treatment biopsy

1

CR

10% tumor necrosis, no individual cell death

20% necrosis, coagulation and edema

Needle core

2

SD

no necrosis or individual cell death

no evidence of tumor cell death

Excisional

3

SD

<5% necrosis with rare individual cell death

60% necrosis with hemorrhage

Excisional

4

SD

no necrosis or individual cell death

40–50% necrosis and hemorrhage with moderate to severe skin necrosis

Excisional

5

SD

no necrosis and moderate cell death

Less than 50% multifocal mild hemorrhage and necrosis

Excisional

6

SD

no necrosis or individual cell death

no necrosis or individual cell death

Excisional

7

PR

no necrosis or individual cell death

no necrosis or individual cell death

Excisional