Table 1 Protein expression differences among experimental groups at different time points (30 min, 1 h, 4 h and 48 h)
From: Changes in serum proteins after endotoxin administration in healthy and choline-treated calves
LPS_Choline | P02081; Hemoglobin fetal subunit beta/1.52 Q9QAQ7; Non structural protein of 4 9 kDa/3.42 P02676; Fibrinogen beta chain/3.83 A2I7N1; Serpin A3 5/1.44 Q3ZC07*; Actin alpha cardiac muscle 1/15.21 Q32L76; Serum amyloid A 4 protein/1.70 A2I7N3; Serpin A3 7/1.44 Q3ZC07*; Actin alpha cardiac muscle 1/187.33 P0CH28*; Polyubiquitin C/1.59 P12799; Fibrinogen gamma B chain/8.44 Q2M2T2; U-p-C19orf71-h/2.17 P02676; Fibrinogen beta chain/64.53 | A2I7N1; Serpin A3 5/1.44 Q9TTK6; Membrane primary amine oxidase/Infinity P01966; Hemoglobin subunit alpha/1.50 P19034; Apolipoprotein C II/2.82 Q9MYP6; beta hydroxysteroid dehydrogenase 14/26.44 Q1JQ97; Bardet Biedl syndrome 4 protein homolog/2.30 Q9TTK6; Membrane primary amine oxidase/11.79 P81644; Apolipoprotein A II/1.45 P19035; Apolipoprotein C III/2.34 Q32L76; Serum amyloid A 4 protein/2.20 Q5E9E3; Complement C1q subcomponent subunit A/3.01 P34955; Alpha 1 antiproteinase/1.60 P28800; Alpha 2 antiplasmin/1.43 P80012; von Willebrand factor Fragment/2.98 | Q9TTE1; Serpin A3 1/2.09 Q80E01; Glutaredoxin 1/2.21 Q3SZJ0; Argininosuccinate lyase/1.81 Q17QL1; Glucosamine 6 phosphate isomerase 2/2.96 Q3T0Z5; Leukocyte receptor cluster m-1-h/2.22 Q9TTE1; Serpin A3 1/1.74 Q9TTK6; Membrane primary amine oxidase/64.58 A2I7N0; Serpin A3 4/1.47 P41361; Antithrombin III/2.67 P00735; Prothrombin/2.287 P12799; Fibrinogen gamma B chain/5.92 | |
LPS | P17697; Clusterin/1.43 Q0V898; Negative elongation factor E/1.68 Q9TTK6; Membrane primary amine oxidase/7.17 A6QPQ2; Serpin A3 8/1.67 O46406; Primary amine oxidase lung isozyme/3.74 P01044; Kininogen 1/2.13 A7E3W2; Galectin 3 binding protein/13.09 P41356; Fusion glycoprotein F0/1.82 O62830-2; Isoform Beta 2 of Protein phosphatase 1B/6.78 Q3T132; Ragulator complex protein LAMTOR2/189.56 Q3SZJ0; Argininosuccinate lyase/9.22 Q9QAQ7; Bovine coronavirus strain OK 0514 GN 4a/4.93 Q0V898; Negative elongation factor E/10.86 Q28901;6-p-2-k-f-2-6-b-f/Infinity | A2I7N2; Serpin A3 6/1.64 P81644; Apolipoprotein A II/1.62 P19035; Apolipoprotein C III/2.80 Q5E9E3; Complement C1q subcomponent subunit A/2.66 Q28901; 6-p-2-k-f-2-6-b-f/infinity P01966; Hemoglobin subunit alpha/1.81 P02081; Hemoglobin fetal subunit beta/1.55 P80109; P-g-s-p-d/1.50 Q5E9F5; Transgelin 2/2.90 P22226; Cathelicidin 1/13.17 Q7SIH1; Alpha 2 macroglobulin/1.41 A2I7M9; Serpin A3 2/9.68 P00924; ENO1 YEAST Enolase 1/1.46 Q3MHN5; Vitamin D binding protein/1.67 Q3ZC07*; Actin alpha cardiac muscle 1/25.52 P80109; Phosphatidylinositol glycan specific phospholipase D/3.11 O02659; Mannose binding protein C/5.76 P0CH28*; Polyubiquitin C/4.09 A8YXX7; Trefoil factor 3/4.93 Q2TBS3; Uncharacterized protein C20orf79 homolog/4.76 Q96629; Adenain/2.23 P19034; Apolipoprotein C II/4.21 Q1JP73; UPF0553 protein C9orf64 homolog/12.57 | Q9TTK6-2; Isoform 2 of Membrane primary amine oxidase/2.30 Q1JP73; UPF0553 protein C9orf64 homolog/1.95 Q56K14; 60S acidic ribosomal protein P1/Infinity Q3SZV7; Hemopexin/2.10 Q1JQ97; Bardet Biedl syndrome 4 protein homolog/1.48 Q56K14;60S acidic ribosomal protein P1/Infinity Q96629; Adenain/1.74 Q2KIT0; Protein HP 20 homolog/1.93 Q5E9F5; Transgelin 2/Infinity P62803; Histone H4/11.67 | |
Choline | O46406; Primary amine oxidase lung isozyme/1.74 Q28901; 6-p-2-k-f-2-6-b-f/Infinity Q2M2T2; Uncharacterized protein C19orf71/1.78 A2I7N3; Serpin A3 7/1.56 Q17QL1; Glucosamine 6 phosphate isomerase 2/1.48 | A5PJC4; Ubiquitin ISG15 c. e. E2 L6/1.45 Q80E01; Glutaredoxin 1/1.40 Q0VCI2; Syntaxin 19/3.81 | Q0V898; Negative elongation factor E/2.4 Q05204; Lysosome associated membrane glycoprotein 1/4.03 Q56K14; 60S acidic ribosomal protein P1/8968.4 P34955; Alpha 1 antiproteinase/1.47 A2I7N2; Serpin A3 6/1.72 Q3SZJ0; Argininosuccinate lyase/1.41 Q17QL1; Glucosamine 6 phosphate isomerase 2/8.44 | |
Control | P80012; von Willebrand factor Fragment/2.08 | A2I7N0; Serpin A3 4/1.60 | P21752; Thymosin beta 10/1.45 | |
Q3SZK0; Solute carrier family 25 member 34/1.72 | Q2TBS3; Uncharacterized protein C20orf79/2.01 | Q3T132; Ragulator complex protein LAMTOR2/2.04 | ||
Q05204; Lysosome associated membrane glycoprotein 1/2.34 | P01044-2*; Isoform LMW of Kininogen 1/2.87 | |||
Q9TTK6-2; Isoform 2 of Membrane primary amine oxidase/2.82 | ||||
Q80E01; Glutaredoxin 1/3.37 | Q58CQ9; Pantetheinase/1.58 | |||
Q05204; Lysosome associated membrane glycoprotein 1/10.89 | Q3MHN5; Vitamin D binding protein/1.48 | |||
Q96629; Adenain/1.69 | ||||
Q2KIU3; Protein HP 25 homolog 2/1.70 | P56652; Inter alpha trypsin inhibitor heavy chain H3/1.58 | |||
P02081; Hemoglobin fetal subunit beta/1.72 | Q29443; Serotransferrin/1.57 | P01044-2*; Isoform LMW of Kininogen 1/1.62 | ||
Q32PJ2; Apolipoprotein A IV/1.45 | Q58CQ9; Pantetheinase/1.84 | |||
A2I7N2; Serpin A3 6/4.57 | P21752; Thymosin beta 10/1.46 | |||
Q2KJF1; Alpha 1B glycoprotein/1.46 | Q9MYP6;17 beta hydroxysteroid dehydrogenase 14/2.24 | |||
P01966; Hemoglobin subunit alpha/1.63 | ||||
P02070; Hemoglobin subunit beta/1.98 | ||||
A7YY73; Transcription factor MafF/5.00 | ||||
E1BF81; Corticosteroid binding globulin/5.27 | ||||
Control | Choline | LPS | LPS_Choline |