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Table 2 Protective efficacy of S06004ΔSPI2. Group A and C were intramuscularly immunized with 2 × 107 CFU S06004ΔSPI2 in 2-day old chickens, group B, D and E were nonimmunized. At 10 dpv, group A–D were challenged

From: Immunogenicity and protective efficacy of Salmonella enterica serovar Pullorum pathogenicity island 2 mutant as a live attenuated vaccine candidate

Group

Vaccination

Number

Challenge

Survivors/Total

Survival rate (%)

Strain

Strain

Route

Dose (CFU)

A

S06004△SPI2

10

S06004

intramuscularly

2 × 109

9/10

90*

B

PBS

10

S06004

intramuscularly

2 × 109

1/10

10

C

S06004△SPI2

10

SG9

intramuscularly

2 × 109

7/10

70*

D

PBS

10

SG9

intramuscularly

2 × 109

0/10

0

E

PBS

10

—

—

—

10/10

100

  1. *P < 0.05 for comparison of group A with group B, and group C with group D
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BMC Veterinary Research

ISSN: 1746-6148

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