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Table 2 Differentially expressed Immune related genes

From: Expression of genes involved in the T cell signalling pathway in circulating immune cells of cattle 24 months following oral challenge with Bovine Amyloidotic Spongiform Encephalopathy (BASE)

Sequence ID

Gene name and function

Log fold change

P value

ENSBTAG00000005892

ZAP70, Zeta-chain (TCR) associated protein kinase 70 kDa

1.81

0.001924

ENSBTAG00000002259

TCRβ, T Cell Receptor Beta Chain

2.66

0.000014

ENSBTAG00000000431

TCRδ, T Cell Receptor Delta Chain

3.18

0.000025

ENSBTAG00000000183

TRAT1, T cell receptor associated transmembrane adaptor 1

2.26

0.000003

ENSBTAG00000011359

CD7, T Cell Antigen CD7

1.75

0.000607

ENSBTAG00000001002

TCF7, T Cell Specific Transcription factor 7

3

0.000025

ENSBTAG00000015710

CD3E, T Cell surface antigen CD3 epsilon chain

3.21

0.000010

ENSBTAG00000021249

LAT, Linker for activation of T cell

2.79

0.000010

ENSBTAG00000012695

LCK, lymphocyte-specific protein tyrosine kinase

1.54

0.000532

ENSBTAG00000006453

CD3g, , T Cell surface antigen CD3 gamma chain

2.11

0.000058

ENSBTAG00000030425

ID3, inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

1.97

0.000710

ENSBTAG00000005990

S1PR1, sphingosine-1-phosphate receptor 1

1.5

0.001691

ENSBTAG00000020319

ALOX5, arachidonate 5-lipoxygenase

−1.85

0.002847

ENSBTAG00000011990

ALOX12, arachidonate 15-lipoxygenase

−2.15

0.000439

ENSBTAG00000001321

Il1β, Interleukin 1 beta

−1.91

0.000644

ENSBTAG00000019428

CCR1, chemokine (C-C motif) receptor 1

−1.41

0.001837

ENSBTAG00000038042

IL8βR, chemokine (C-X-C motif) receptor 2 (CXCR2)

−1.96

0.004877

ENSBTAG00000003305

NCF1, neutrophilcytosolicfactor 1

−2.04

0.000868

ENSBTAG00000037735

C5L2, G protein-coupled receptor 77 (GPR77)

−1.76

0.000958

ENSBTAG00000027051

PTAFR, platelet-activating factor receptor

−1.41

0.000081

ENSBTAG00000004322

FOS, murine osteosarcoma viral oncogene homolog

−1.57

0.000152