Oral immunization with an attenuated Salmonella Gallinarum mutant as a fowl typhoid vaccine with a live adjuvant strain secreting the B subunit of Escherichia coliheat-labile enterotoxin

Table 3 SG-antigen-specific immune responses after prime -boost immunization in experiment 2

Group	n	LPA		Plasma IgG (μg/ml)				Intestinal sIgA (μg/ml)
Group	n	3 wppi	3 wpbi	0 wppi	3 wppi	8 wppi	3 wpbi	0 wppi	3 wppi	8 wppi	3 wpbi
I	5	2.6±1.0^*	2.4±0.7^*	73.8±32.9	182.9±9.9^**	138.5±12.2^**	174.6±29.5^**	4.3±0.6	9.3±0.8^*	5.5±0.7	8.9±1.3^*
II	5	2.1±0.2^*	2.3±0.3^*	75.7±43.9	171.7±23.2^**	132.2±5.2^**	177.8±14.0^**	4.0±0.2	5.5±0.3	5.7±0.3	6.5±0.6
III	5	1.2±0.4	1.1±0.1	41.4±11.5	40.1±18.3	30.5±12.1	36.5±17.7	4.5±0.6	4.8±0.2	4.3±0.1	4.6±0.4

Group I chickens were primed and boosted with a JOL916-JOL1229 mixture, group II chickens were primed and boosted with SG9R, and group III chickens were inoculated with PBS as a control. LPA, lymphocyte proliferation assay. wppi, week post-prime-immunization. wpbi, week post-boost-immunization. Values represent stimulation index mean ± SEM. Asterisks indicate a significant difference compared to the control group (^*p < 0.05, ^**p < 0.01). n, numbers of the chickens used.

ISSN: 1746-6148