From: Expression of autophagy-related protein beclin-1 in malignant canine mammary tumors
Variables | p value |
---|---|
Age (> 11 years vs. ≦ 11 years) | 0.001* |
Tumor size (> 3 cm vs. ≦ 3 cm) | 0.042* |
Tubular formation (> 10% vs. ≦ 10%) | <0.001* |
Nuclear pleomorphism (high vs. low) | 0.044* |
Mitotic count (> 11 vs. ≦ 10/10 HPFs) | 0.005* |
Histologic grade (3 vs. 2 and 1) | <0.001* |
Lymphovascular invasion (yes vs. no) | <0.001* |
Necrosis (extensive vs. limited/no) | 0.004* |
Estrogen receptor (negative vs. positive) | 0.180 |
Her2/neu overexpression (positive vs. negative) | 0.348 |
Beclin-1 cytoplasmic expression (low vs. high) | <0.001* |
Beclin-1 nuclear expression (low vs. high) | 0.074 |