Table 6 Breed-wise average allele frequencies in the high and low risk breed dataset
From: The ESR1 gene is associated with risk for canine mammary tumours
SNP | Allele frequency (minor allele) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Minor allele | Boxer | Cocker Spaniel | Dachshund | English Setter | Standard Poodle | Beagle | Bernese Mountain Dog | Collie | Shetland Sheepdog | |
BRCA2 5UTR | T | 0.138 | 0.589 | 0.682 | 0.177 | 0.167 | 0.244 | 0.904 | 0.524 | 0.330 |
BRCA2 EX 5 | C | 0.130 | 0.848 | 0.292 | 0.160 | 0.720 | 0.141 | 0.684 | 0.055 | 0.011 |
BRCA2 EX 11 | G | 0.202 | 0.141 | 0.417 | 0.020 | 0.100 | 0.160 | 0.245 | 0.556 | 0.436 |
BRCA2 INT 18-19 | G | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.463 | 0.117 |
BRIP1 INT 8-9a | G | 0.660 | 0.000 | 0.021 | 0.000 | 0.010 | 0.021 | 0.020 | 0.000 | 0.000 |
BRIP1 INT 15-16 | T | 0.652 | 0.000 | 0.021 | 0.000 | 0.010 | 0.021 | 0.020 | 0.000 | 0.000 |
BRIP1 EX 19b | T | 0.872 | 0.705 | 0.187 | 0.120 | 0.837 | 0.489 | 0.204 | 0.033 | 0.809 |
CHEK2 INT 5-6 | G | 0.033 | 0.159 | 0.073 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
CHEK2 INT 8-9 | G | 0.670 | 0.120 | 0.271 | 0.270 | 0.050 | 0.064 | 0.073 | 0.000 | 0.021 |
ESR1 EX 2 | T | 0.967 | 0.772 | 0.729 | 0.410 | 0.310 | 0.670 | 0.102 | 0.213 | 0.234 |
ESR1 EX 4 | G | 0.011 | 0.043 | 0.000 | 0.000 | 0.240 | 0.053 | 0.000 | 0.791 | 0.766 |
ESR1 INT 7-8a | A | 0.000 | 0.083 | 0.044 | 0.600 | 0.000 | 0.000 | 0.942 | 0.000 | 0.000 |
ERBB2 INT1-2 | T | 0.106 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
ERBB2 INT 3-4 | G | 0.033 | 0.326 | 0.365 | 0.720 | 0.173 | 0.223 | 0.918 | 0.637 | 0.936 |
ERBB2 INT 8-9 | G | 0.043 | 0.318 | 0.052 | 0.020 | 0.000 | 0.109 | 0.000 | 0.000 | 0.000 |
ERBB2 INT 12-13b | A | 0.915 | 0.533 | 0.542 | 0.240 | 0.230 | 0.798 | 0.071 | 0.225 | 0.043 |
ERBB2 EX 13a | G | 0.223 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.020 | 0.000 | 0.000 |
ERBB2 EX 13b | T | 0.926 | 0.533 | 0.531 | 0.240 | 0.230 | 0.798 | 0.071 | 0.233 | 0.043 |
ERBB2 EX 14 | A | 0.021 | 0.250 | 0.260 | 0.460 | 0.260 | 0.170 | 0.561 | 0.451 | 0.870 |
PTEN INT 3-4 | G | 0.021 | 0.413 | 0.031 | 0.450 | 0.040 | 0.128 | 0.000 | 0.538 | 0.734 |
PTEN INT 7-8 | A | 0.000 | 0.076 | 0.000 | 0.470 | 0.340 | 0.128 | 0.010 | 0.544 | 0.766 |
PTEN EX 9 | T | 0.000 | 0.076 | 0.000 | 0.450 | 0.020 | 0.128 | 0.000 | 0.538 | 0.734 |
STK11 INT 1-2 | T | 0.394 | 0.348 | 0.156 | 0.010 | 0.310 | 0.213 | 0.745 | 0.467 | 0.011 |