Figure 2From: Bilateral central pain sensitization in rats following a unilateral thalamic lesion may be treated with high doses of ketamineHeat sensitivity evaluated with Hargreave’s test in Spraque-Dawley rats. Animals received stereotaxically either saline (n = 8) or a collagenase solution (n = 7) in the ventroposterolateral nucleus of the thalamus. No significant difference in the thermal thresholds between both groups was seen at baseline and at different post surgical time points up to 22 days (F1,13 = 0.23, ns).Back to article page