Figure 4From: The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitrop53 protein accumulation in untreated osteosarcoma cells. Representative photomicrographs of cells probed with an antibody against p53 protein show strong accumulation in HMPOS cells, moderate staining in Clone-4 and none in the D17 and COS cell lines. The signal that can be observed in D17 and COS cells is the counterstain hematoxylin (see methods).Back to article page