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Table 1 Summary of data for dogs with DFI > 300 and DFI < 100 days, including HES1 immunohistochemistry score

From: HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

Breed

Age at Dx (yrs)

Sex

Tumor Loc

DFI (days)

Avg% stain

Avg stain intensity

Total score

Greyhound

4.4

MC

PH

40

1

1

1

Rottweiler

5

MC

DF

69

3

3

9

Greyhound

7

MC

DF

77

2

1

2

Mix

9

FS

T

90

2

1

2

Greyhound

8

FS

PT

94

1

2

2

Labrador

10.2

FS

DH

95

3

3

9

Mix

8.8

MC

DF

97

2

1

2

Golden

10.8

MC

PH

97

2

1

2

Mix

7.6

FS

DR

307

2

2

4

Greyhound

7.1

MC

PH

467

1

1

1

Mix

12.4

MC

DR

694

3

3

9

Malamute

10.1

FS

DR

734

3

2

6

Labrador

8.7

MC

T

787

3

3

9

Golden

8

FS

DR

885

3

2

6

  1. DFI disease free interval, Dx diagnosis, MC male castrated, FS female spayed, P proximal, D distal, H humerus, R radius, T tibia, Total Score is product of scores for % cells staining and staining intensity.
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BMC Veterinary Research

ISSN: 1746-6148

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