Figure 7From: HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumorsHigh HES1 immunoreactivity score correlates with lower histologic grade and improved outcome in canine osteosarcoma. Kaplan-Meier plot of disease free interval based on HES1 immunoreactivity score. Dogs with high HES1 scoring tumors (score ≥ 4, n = 28) had a statistically significantly longer disease free interval than dogs with low HES1 scoring tumors (score < 4, n = 33) (p = 0.0023, Log Rank test).Back to article page