Table 3 Unbiased PK deficiency allele frequencies in 12 cat breeds based on samples submitted for other genetic testing
From: Erythrocyte Pyruvate Kinase Deficiency mutation identified in multiple breeds of domestic cats
Non - PK deficiency submitted samples (unbiased) | ||||||||
|---|---|---|---|---|---|---|---|---|
Breed | # | GG | GA | AA | Freq. A | Exp GG | Exp GA | Exp AA |
Abyssinian | 497 | 445 | 52 | 0 | 0.0523 | 447 | 49 | 1 |
Bengal | 320 | 242 | 73 | 5 | 0.130 | 242 | 72 | 5 |
Domestic SH/LH | 76 | 62 | 13 | 1 | 0.12 | 59 | 16 | 1 |
Egyptian Mau | 36 | 27 | 9 | 0 | 0.13 | 27 | 8 | 1 |
Maine Coon | 118 | 103 | 15 | 0 | 0.0636 | 103 | 14 | 0 |
Exotic SH | 645 | 644 | 1 | 0 | 0.000775 | 644 | 1 | 0 |
Norwegian Forest Cat | 13 | 10 | 3 | 0 | 0.12 | 10 | 3 | 0 |
Oriental SH | 337 | 336 | 1 | 0 | 0.00148 | 336 | 1 | 0 |
Persian | 2226 | 2217 | 9 | 0 | 0.002021 | 2217 | 9 | 0 |
Savannah | 11 | 10 | 1 | 0 | 0.046 | 10 | 1 | 0 |
Siberian | 377 | 360 | 16 | 1 | 0.0239 | 359 | 18 | 0 |
Somali | 227 | 213 | 14 | 0 | 0.0308 | 213 | 14 | 0 |
unreported | 111 | 98 | 13 | 0 | 0.0586 | 98 | 12 | 0 |
Total | 4994 | 4767 | 220 | 7 | 0.0234 | 4763 | 229 | 3 |
Total (−Per, OSh, ExSh) | 1786 | 1570 | 209 | 7 | 0.06234 | 1570 | 209 | 7 |