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Table 4 Immunostaining score values for MMPs and TIMP-2 in benign and malignant mammary tumors, expressed as the median (range).

From: Matrix metalloproteinases and their inhibitors in canine mammary tumors

Protein

Immunostaining score values

(median and range)

p values

 

Benign tumors

Malignant tumors

 

MMP-2

58.5 (45.4-145.5)

179.4 (120.1-267.3)

0.002

MMP-9

78 (26.8-189)

101.1 (34.3-213.9)

0.01

MMP-13

84.2 (0-198.2)

45.3 (0-101.2)

0.005

MT1-MMP

65.3 (0-230.2)

132.1 (34.2-221.2)

0.002

TIMP-2

74.3 (21.2-201.2)

48.9 (0-136.6)

n.s.

  1. n.s. = not significant