From: Accumulation and dissemination of prion protein in experimental sheep scrapie in the natural host
Group | Challenge | Age at challenge (days) | Attack rate | Mean incubation period (days) Range, (SD) |
---|---|---|---|---|
1 | 1 g RBP1 oral | 14 | 25/25 | 192 185–204, (6.9) |
2 | 5 g RBP1 oral | 14 | 28/28 | 185 178–198, (7.4) |
3 | 1 g RBP1 oral (after 3 g scrapie negative sheep brain) | 245 | 8/8 | 345 198–639, (186) |
4 | Exposure to groups 1 and 2 | 42 days onwards | 4/4 | 649* 592–716, (61) |
5 | 3 g Scrapie negative sheep brain | 14 days | 8/8 | 1085** 880–1231 (156) |