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Table 4 Bone marrow plasma cell percentage before and after VDC-1101 in 3 dogs experiencing stringent complete response

From: GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma

 

Pre-treatment

Following final treatment

Patient AM

No marrow elements present

2% well-differentiated plasma cells

Patient KW

40-50% atypical plasma cells

<1% morphologically normal plasma cells

Patient SR

30% atypical plasma cells

2-5% well-differentiated plasma cells

  1. NB: patient AM’s myeloma diagnosis was made based on hypercalcemia, monoclonal gammopathy and the presence of multiple bony lytic lesions on radiographs.
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BMC Veterinary Research

ISSN: 1746-6148

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