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Fig. 5 | BMC Veterinary Research

Fig. 5

From: Differential proteomic analysis demonstrates follicle fluid participate immune reaction and protein translation in yak

Fig. 5

Networks of the protein-protein interaction (PPI) of the differentially expressed proteins (DEPs) enriched by Gene Ontology (GO) enrichment analysis and subsequently screened by Molecular Complex Detection (MCODE) plugin of Cytoscape. The functional modules of the PPI network were shown in the clusters. a Network of the PPI for the up-regulated DEPs in the mature FF. The cluster 1 takes parts in defense response, acute-phase response, and acute inflammatory response. The cluster 2 participates in defense response, acute-phase response, response to other organism, and acute inflammatory response, and response to biotic stimulus. The cluster 3 plays roles in complement activation. b Network of the PPI for down-regulated DEPs in the mature FF. The cluster 4 participates in translation, peptide biosynthetic process, peptide metabolic process, and amide biosynthetic process. The cluster 5 takes parts in DNA geometric change, DNA conformation change, and DNA duplex unwinding. The cluster 6 performs its functions in Golgi vesicle transport, cellular protein localization, and cellular macromolecule location

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