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Table 4 Indices of biological variation of fasting insulin concentrations and HOMA-IR in 7 cats (5 lean (BCS = 3/5) and 2 overweight (BCS = 4/5)) sampled once a week for 5 weeks

From: Homeostasis model assessment, serum insulin and their relation to body fat in cats

 

HOMA-IR

All cats (n = 7)

HOMA-IR

Lean cats (n = 5)

Insulin (mU/L)

All cats (n = 7)

Insulin (mU/L)

Lean cats (n = 5)

Mean

0.78

0.63

3.8

3.2

Range

0.1–2.2

0.1–1.3

0.6–9.8

0.6–6.5

CVG % (95% CI)

52.3 (0-87.7)

51.0 (0-90.1)

54.4 (0-91.2)

52.1 (0-92.1)

CVI % (95% CI)

51.0 (33.4–65.4)

38.2 (22.1–50.2)

48.7 (32.1–62.3)

38.0 (22.1–49.9)

CVA % (95% CI)

7.4 (5.9–9.7)

7.4 (5.8–10.3)

6.6 (5.3–8.6)

6.6 (5.2–9.2)

RCV increase (%)

385

284

364

281

RCV decrease (%)

26

35

27

36

II

1.0

1.31

1.11

1.35

  1. CVGindicates between-cat coefficient of variation; CVI within-cat coefficient of variation; CVA analytical coefficient of variation derived from the mixed model analysis; RCV reference change value based on \(RCV \left(\%\right)=100 \text{e}\text{x}\text{p}(\pm 1.96 \sqrt{ 2\left({SD}_{I}^{2}(\text{ln}x\right)+{SD}_{A}^{2}(\text{ln}x\left)\right)}\) ; II, index of individuality based on CVG/(CVI2 + CVA2)0.5