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Table 2 Prevalence of rescue analgesia according to the route of administration and timepoints in dogs undergoing ovariohysterectomy and administered buprenorphine (Simbadol; 0.02 mg/kg) by the intravenous (IV), intramuscular (IM) or subcutaneous (SC) routes of administration

From: Pharmacokinetics and analgesic effects of intravenous, intramuscular or subcutaneous buprenorphine in dogs undergoing ovariohysterectomy: a randomized, prospective, masked, clinical trial

Route of administration

Baseline (hours)

Postoperative time points after extubation (hours)

Total

0

0.5

1

2

3

4

6

8

12

24

IV

8

1

1

0

0

0

0

0

0

0

2

IM

8

1

1

1

0

0

0

0

0

0

3

SC

8

4

1

1

0

1

0

0

0

0

7