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Table 4 Experimental set up for the titration of highly HEV positive liver tissue in log steps in the porcine model

From: High sensitivity of domestic pigs to intravenous infection with HEV

Exp. No.

Dilution = Group

Animal identity

Animals

Sex

Age at inoculation

Observation period

infected

horizontal control

in weeks

1

10−2

Pig T1–11, −12, −13, −14

4

f/m

10

27dpi

10−3

Pig T1–07, −08, −09, −10,

4

f/m

10

27dpi

10−4

Pig T1-01c -02c,-03, −04, −05, −06

4

2

f/m

10

27dpi

2

10−4

Pig T2–29, −30, −31, −32

4

m

11

91dpi

10−5

Pig T2–25, −26, −27, −28

4

f/m

11

49dpi

10−6

Pig T2–21, −22, −23, −24

4

f

11

63dpi

10−7

Pig T2–17, −18, −19, −20

4

f/m

11

63dpi

10−8

Pig T2–13, −14, −15, −16

4

m

11

77dpi

10−9

Pig T2–09, −10, −11, −12

4

f

11

77dpi

  1. The dilution step of the homogenate as assigned the group designation, f-female, m-male, dpi-days post infection, −- none