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Table 2 ORF5 nucleotide (NT) and amino acid (AA) sequence similarity of subtype 1/subgroups of type 1 PRRSV (A) and lineages of type 2 PRRSV (B) to prototypes/vaccine strains

From: Geographic distribution and molecular analysis of porcine reproductive and respiratory syndrome viruses circulating in swine farms in the Republic of Korea between 2013 and 2016

Type

Isolated year

Subtype /Lineage

Sequence similarity

prototype

Vaccine strain

Lelystad virus

DV (Porcilis® PRRS)

VP-046 (UNISTRAIN® PRRS)

(A)

1

2005-2009

subtype 1-A

87.8-90.9 (86.1-91.6)a

87.6-91.1 (86.1-91.6)

86.8-89.8 (85.6-91.1)

subtype 1-B

85.8-86.9 (85.2-89.1)

85.3-86.8 (84.2-88.1)

85.5-87.5 (85.2-88.6)

2013-2016

subtype 1-A

84.9-89.8 (82.2-91.6)

85.0-89.6 (82.2-90.6)

84.2-88.9 (81.7-92.6)

subtype 1-B

86.0 (85.6)

85.5 (84.7)

85.5 (86.1)

subtype 1-C

93.9-98.4 (90.1-96.5)

93-4-99.5 (89.6-98.5)

93.7-99.8 (90.6-99.5)

Type

Isolated year

Subtype /Lineage

Sequence similarity

prototype

Vaccine strain

VR2332

Ingelvac PRRS MLV (Ingelvac® PRRS MLV)

P129 (Fostera® PRRS)

(B)

2

2003-2010

lineage 4

88.9 (88.1) b

88.9 (88.6)

89.7 (89.1)

lineage 5

88.9-99.5 (88.1-99.0)

89.9-99.8 (87.6-99.5)

88.2-91.9 (88.1-92.5)

lineage kor A

87.6-89.6 (82.6-88.6)

86.7-89.7 (84.1-91.5)

87.2-90.2 (86.1-93.0)

lineage kor C

84.7-87.1 (84.1-88.6)

84.7-87.1 (83.6-88.1)

85.4-88.1 (84.1-89.1)

2013-2016

lineage 1

82.3-86.9 (81.7-87.6)

84.9-86.1 (83.1-85.6)

85.2-86.6 (84.6-86.6)

lineage 5

87.6-99.3 (85.6-99.0)

87.9-99.7 (87.1-99.5)

86.7-91.7 (84.6-91.5)

lineage kor A

85.1-89.1 (82.1-87.6)

85.4-88.7 (82.6-88.1)

85.6-89.2 (85.1-90.1)

lineage kor B

85.7-89.1 (83.6-90.1)

85.7-89.1 (83.1-89.6)

86.1-89.1 (85.1-89.1)

lineage kor C

85.2-86.4 (83.6-86.1)

83.6-87.6 (81.2-87.1)

82.6-86.9 (81.6-87.6)

  1. aNT and AA sequence similarity to Type 1 PRRSV prototypes (Lelystad) and vaccine strains (DV and VP-046). Parenthesis indicates AA sequence similarity
  2. bNT and AA sequence similarity to Type 2 PRRSV prototypes (VR2332) and vaccine strains (Ingelvac PRRS MLV, P129). Parenthesis indicates AA sequence similarity