Effects of isoflurane, sevoflurane, propofol and alfaxalone on brain metabolism in dogs assessed by proton magnetic resonance spectroscopy (1H MRS)

Table 7 pulse rate and body temperature

		pre induction	post induction	measurement 1	measurement 2	measurement 3
		Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD	Mean ± SD
pulse rate [bpm]	Isoflurane	92.40 ± 18.23	123.90 ± 24.92*^A	113.13 ± 8.81^AB	125.29 ± 14.15*^A	131.45 ± 15.44*^AB
	Sevoflurane	96.00 ± 15.00	123.90 ± 14.52*^A	104.65 ± 13.83^AB	116.08 ± 11.94*^A	127.37 ± 18.57*^A
	Propofol	87.20 ± 8.85	98.70 ± 26.96^A	90.11 ± 22.37^A	100.47 ± 21.31^A	103.20 ± 19.75
	Alfaxalone	94.00 ± 7.24	163.20 ± 29.47*	115.68 ± 26.35^B	155.55 ± 37.31*	149.94 ± 19.40*^B
body temperature [°C]	Isoflurane	38.48 ± 0.28	38.18 ± 0.53	37.31 ± 0.57*	37.25 ± 0.67*^AB	36.93 ± 0.60*^A
	Sevoflurane	38.46 ± 0.21	38.07 ± 0.51	37.24 ± 0.32*	37.02 ± 0.38*^A	36.83 ± 0.41*^A
	Propofol	38.39 ± 0.27	38.08 ± 0.53	37.71 ± 0.45*	37.84 ± 0.46*^B	38.20 ± 0.37
	Alfaxalone	38.52 ± 0.30	38.26 ± 0.36	37.38 ± 0.54*	37.22 ± 0.63*^AB	37.03 ± 0.66*^A

Mean ± SD pulse rate [bpm] and body temperature [°C] pre and post induction and averaged over measurement period 1, 2 and 3. * p < 0.05 significant to baseline (pre induction) within one treatment and different alphabetical superscripts differ significantly between treatments at the same timepoint (p < 0.05)

ISSN: 1746-6148