Fig. 2
Effect of cortisol on PGE2 and cytokine production in LPS-stimulated RAW 264.7 macrophages. RAW264.7 cells were co-treated with cortisol (0, 5, 15 and 30 ng/mL) and LPS (1 μg/mL) for 0, 6, 12, and 24 h. Levels of PGE2 (a), IL-1β (b), IL-6 (c), and TNFα (d) in culture supernatants were measured by ELISA. The data presented are the means±SEM. ** p < 0.01 vs. the control group; # p < 0.05, ## p < 0.01 vs. the LPS group