Fig. 4
From: Solid type primary intraosseous squamous cell carcinoma in a cat
Primary intraosseous squamous cell carcinoma (PIOSCC) of the mandible in the cat. a Sheets of polygonal neoplastic cells with eosinophilic, nongranulated cytoplasm and round to oval nuclei with prominent nucleoli are evident infiltrating the bony tissue. A focus of dyskeratotic neoplastic cells is present in the left bottom corner. HE. Bar = 100 μm b The neoplastic cells exhibit a moderate to marked positive cytoplasmic reaction for cytokeratin. Immunohistochemistry for cytokeratin. Bar = 100 μm