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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Improved yield of canine islet isolation from deceased donors

Fig. 2

Immunohistochemistry of canine pancreas by region. Tissue sections of the three major regions of the pancreas were stained with antibodies for insulin (top row), somatostatin (center row), and glucagon (bottom row) to identify the three major islet cell types (beta, delta, and alpha cells, respectively). Insulin positive cells were primarily located in the body (center column) and tail (right column), with the highest concentration and largest sized clusters in the tail. Insulin positive cells in the head of the pancreas (left column) were far less prevalent and occurred primarily in very small clusters or single cells. Similar patterns were observed for somatostatin, while glucagon positive cells were present in extremely low numbers in the head and body and often appeared as isolated single cells. Glucagon images are displayed at higher magnification to better illustrate single cells. Scale bars = 200 μm

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