Fig. 4
The probability distribution of the calculated %TMIC for cefquinome using a 10,000-subject Monte Carlo analysis based on the measured PK parameters obtained following IM injection at 2 mg/kg BW with 24-h (a and b) and 12-h (c and d) dosing interval in black swans and E. coli MIC distribution in this study. The areas of blue columns represent the probability of target attainment (PTA) for %TMIC ≥ 50 or 80%