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Table 8 Sensitivity, specificity, positive and negative predictive value, and overall accuracy of the real-time RT-PCR

From: Sensitivity and specificity of a real-time reverse transcriptase polymerase chain reaction detecting feline coronavirus mutations in effusion and serum/plasma of cats to diagnose feline infectious peritonitis

 

effusion

serum/plasma

sensitivity % (95% CI)

68.6 (50.7–83.2)

0 (0–23.2)

specificity % (95% CI)

95.8 (78.9–99.9)

n.d.

NPV % (95% CI)

67.6 (49.5–82.6)

17.6 (3.8–43.4)

PPV % (95% CI)

96.0 (80.0–99.9)

n.d.

overall accuracy % (95% CI)

79.7 (67.2–89.0)

17.6 (3.8–43.4)

FIP prevalence %

59.3

82.4

  1. FIP feline infectious peritonitis, n.d. not determined, NPV negative predictive value, PPV positive predictive value, RT-PCR reverse transcriptase polymerase chain reaction, 95% CI 95% confidence interval