Critically appraised topic on adverse food reactions of companion animals (4): can we diagnose adverse food reactions in dogs and cats with in vivo or in vitro tests?

Table 1 Number of tested animals and type of test performed

Reference	Dogs/Cats with AFR	Control dogs/cats ^a	Type of test evaluated	Diet & provocation details known?
Allenspach et al. 2006 [22]	9 D	5 D	CT	Yes
Belova et al. [21]	15 C	114 C	IgE	No
Bethlehem et al. 2012 [5]	18 D	18 D	PT, IgG, IgE	Yes
Coyner & Schick 2016 [26]	1 D	6 D	HT, ST	No
Devaud et al. 2009 [20]	5 D	7 D	LT	Yes
Elwood et al. 1994 [19]	8 D		GT
Favrot et al. 2017 [24]	14 D	32 D	IgE	No
Foster et al. 2003 [23]		91 D	IgE, IgG	No
Fujimura et al. 2011 [18]	13 D	12 D	IgE, LT	No
Guilford et al. 2001 [17]	16 C	39 C	GT, IgE	Yes
Hardy et al. 2014 [16]	8 D	43 D	IgG, IgE	No
Ishida et al. 2004 [14]	11 D		IDT, IgE, LT	Yes
Ishida et al. 2012 [15]	3 C		IDT, IgE, LT	Yes
Jackson et al. 2003 [13]	14 D		IDT, IgE	Yes
Jeffers et al. 1991 [4]	13 D		IDT, IgE	Yes
Johansen et al. 2017 [25]	24 D		PT	Yes
Kang et al. 2014 [12]		101 D	IgE	No
Kawano et al. 2013 [11]	12 D (no rechallenge)		IgE, LT	No
Kunkle & Horner 1992 [3]	9 D	61 D	IDT	No
Mueller & Tsohalis 1998 [6]	8 D	8 D	IgE	Yes
Ohmori et al. 2007 [10]	1 D		IDT, IgE	Yes
Puidgemenot et al. 2006 [9]	9 D	3 D	IDT	Yes
Vaden et al. 2000 [8]	6 D		GT, IgE	Yes
Wilhelm & Favrot 2005 [1]	5 D	32 D	IgE, IgG	No

C cat, D dog, GT gastroscopic food sensitivity testing, HT hair testing, IDT intradermal testing with food antigens, IgG serum testing for food-specific IgG, IgE serum testing for food-specific IgE, PT patch testing with food antigens, ST salivary testing
^ahealthy or allergic, but not adverse food reaction

ISSN: 1746-6148