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Table 1 Precision of CRP determination in pooled serum samples with CRP concentrations below a clinical decision limit (A1 - A2) as well as pooled serum samples with clinically relevant CRP concentrations

From: Evaluation of a species-specific C-reactive protein assay for the dog on the ABX Pentra 400 clinical chemistry analyzer

  Intra-assay CV Inter-assay CV
Between run CV Between day CV
Level Mean CRP concentration (mg/l) SD (mg/l) CV% SD (mg/l) CV% SD (mg/l) CV%
A1 2.3 0.72 31.1 n.d. n.d. n.d. n.d.
A2 3.8 0.35 9.3 n.d. n.d. n.d. n.d.
A 7.2 0.87 12.1 0.56 7.8 0.44 6.1
B 58.4 1.08 1.9 1.25 2.1 2.7 4.6
C 103.9 0.88 0.9 0.91 0.9 1.9 1.8
D 272.1 1.85 0.7 4.98 1.8 2.8 1.1
  1. A1, A2: CVs for intra-assay imprecision of two canine serum pools analyzed 20 times in a single run without recalibration.
  2. A – D: Inter- and intra-assay CVs of 6 canine serum pools analyzed in duplicates twice daily over 5 days.
  3. CVs not fulfilling the quality specifications i.e., are higher than 12.2% [32] are marked in bold letters.Abbreviations: n.d. = not done, SD = standard deviation; CV = coefficient of variation.