From: First clinical case report of Cytauxzoon sp. infection in a domestic cat in France
Day (D) | Findings | Treatment | |
---|---|---|---|
Clinical observation | Clinical investigation | ||
D-14 | Clinical history: hyperthermia (41 °C), lethargy, anorexia, dehydration and weight loss after 4 days vagrancy | amoxicillin (10 mg/kg) + clavulanic acid (2.5 mg/kg) orally every 12 h for 10 days. | |
D0 | hyperthermia (40.5 °C), abdominal pain and subcutaneous hematomas on the abdomen | marbofloxacin (2 mg/kg) and carprofen (4 mg/kg) marbofloxacin (2 mg/kg PO once daily for 10 days meloxicam 0.05 mg/kg PO once daily for 5 days | |
D7 to D29 | neutrophilic leukocytosis at the complete blood counts (CBC), biochemical, serological and molecular analyses for different infectious disease: all negative Abdominal, pulmonary and oral X-ray: normal except a marked splenomegaly oropharyngeal swab for the detection of calicivirus and feline herpes virus were conducted | ||
D29 | no clinical improvement vomiting, stomatitis, abdomen pain, hyperthermia, anorexia, severe depression | Stained blood smear of peripheral blood: small inclusions within erythrocytes PCR identification of Cytauxzoon sp. | imidocarb dipropionate 3.5 mg/kg/ subcutaneous injection). |
Day 37 | Clinical improvement | Inclusions present in the blood smear | |
Day 46 | Excellent general conditions | No more inclusions in the blood smear | |
Day 63 | Relapse: hyperthermia, anorexia depression and stomatitis | Inclusions present in the blood smear PCR positive for Cytauxzoon sp. | imidocarb dipropionate 3.5 mg/kg/ subcutaneous injection). |
Day 69 | Clinical recovery | hypergammaglobulinemia with hyperproteinemia (91 g/L; reference range: 57 – 94 g/L) with an hematocrit at the lower limit of the reference range (28 L/L; reference range: 28 – 45). Absence of inclusion in the blood smear | |
Day 76 | Death by car accident |